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Recent News and Articles on the Keywords: lung cancer + radiation + cancer  Related to the article below (Last Update: 5/5/2008)

Cancer center aims to be the area?s best
Brazosport Facts (subscription), TX - May 4, 2008
Bonnen anticipates the new radiation treatment system also can fight cancer in fewer treatments than the current one. ?For early stage lung cancer, ...
Rain doesn?t wash away walkers? dedication to Brockton cancer walk
Wicked Local Brockton, MA -
It?s that kind of progress like that encourages Katie Moody, who was only 23 when she lost her mother, Ann Marie Redd, to a case of lung cancer that killed ...
OXiGENE Reports First Quarter 2008 Results
FOXBusiness -
About OXiGENE OXiGENE is a clinical-stage biopharmaceutical company developing novel therapeutics to treat cancer and eye diseases. ...OXGN
Daughter files suit to help father who lived in Los Alamos
Las Cruces Sun-News, NM - May 4, 2008
"Breast cancer, brain cancer, breast cancer, lung cancer, lymphoma, brain cancer ..." she said. Loss said she keeps an obituary scrapbook in hopes the ...
EPA Urges All Americans: Cast Your Vote Now Against Skin Cancer ...
U.S. EPA.gov (press release), DC -
There are more new cases of skin cancer each year than the number of breast, prostate, lung, and colon cancer cases combined. This special month always ...
Cancer survivors prescribe humor
Washington Times, DC - May 3, 2008
Irena Monticelli, diagnosed with lymphoma in 2006, created the book with sisters Rachel and Felicia, who has lung cancer, to offer some comic relief from ...
Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment ...
RedOrbit, TX - May 3, 2008
On the basis of these trial results, bevacizumab in combination with chemotherapy received FDA approval for use in lung cancer. RADIATION THERAPY The first ...
Family seeks help through cancer struggle
South Washington County Bulletin, MN - May 2, 2008
It wasn?t just a slipped disc or strained muscle causing him pain ? it was cancer. Diagnosed in February with lung cancer, the normally healthy couple and ...
Teen organizes music fest for cancer research
Galesburg Register-Mail, IL - May 2, 2008
Robert Perkins was diagnosed with lung cancer in mid-1999. Despite chemotherapy and radiation treatments, the cancer spread to his spine and Perkins was ...
New drug for cancer in 5 years
Scotland on Sunday, UK - May 3, 2008
Theoretically, a drug containing Nutlin 3 could be used to help treat virtually all types of cancer, including lung, leukaemia, breast and colon. ...
Source: Google News

… in Regionally Advanced Unresectable Non-Small Cell Lung Cancer* Radiation Therapy Oncology Group, … -
W Sause, P Kolesar, S Taylor, D Johnson, R … - Chest, 2000 - Am Coll Chest Phys
... Med 115,681-686[ISI][Medline]; Mattson, K, Holsti, LR, Holsti, P, et al (1988)
Inoperable non-small cell lung cancer: radiation with or without chemotherapy. ...

… Results of a Phase III Trial in Regionally Advanced, Unresectable Non-Small-Cell Lung Cancer -
WT Sause, C Scott, S Taylor, D Johnson, R … - jnci, 1995 - jnci.oxfordjournals.org
... Byhardt, AR Dar, and A. Turrisi III Final Results of Phase III Trial in Regionally
Advanced Unresectable Non-Small Cell Lung Cancer: Radiation Therapy Oncology ...

… chemotherapy plus high-dose radiation versus radiation alone in stage III non-small-cell lung cancer -
RO Dillman, SL Seagren, KJ Propert, J Guerra, WL … - New England Journal of Medicine, 1990 - content.nejm.org
... Final Results of Phase III Trial in Regionally Advanced Unresectable Non-Small Cell
Lung Cancer: Radiation Therapy Oncology Group, Eastern Cooperative Oncology ...

… Survival in Stage III Non-Small-Cell Lung Cancer: Seven-Year Follow-up of Cancer and Leukemia Group … -
RO Dillman, J Herndon, SL Seagren, WL Eaton, MR … - jnci, 1996 - jnci.oxfordjournals.org
... R. Bueno High Risk of Brain Metastases in Surgically Staged IIIA Non-Small-Cell
Lung Cancer Patients Treated With Surgery, Chemotherapy, and Radiation J. Clin. ...

… With Mitomycin, Vindesine, and Cisplatin in Unresectable Stage III Non-Small-Cell Lung Cancer -
K Furuse, M Fukuoka, M Kawahara, H Nishikawa, Y … - Journal of Clinical Oncology, 1999 - jco.ascopubs.org
... of chemotherapy/radiation therapy combination for favorable patients with locally
advanced inoperable non-small cell lung cancer: Radiation Therapy Oncology ...

… Cell Lung Cancer Cells and Promotes Cellular Survival and Resistance to Chemotherapy and Radiation -
J Brognard, AS Clark, Y Ni, PA Dennis - Cancer Research, 2001 - AACR
... Akt/Protein Kinase B Is Constitutively Active in Non-Small Cell Lung Cancer Cells
and Promotes Cellular Survival and Resistance to Chemotherapy and Radiation. ...

Inoperable non-small cell lung cancer: radiation with or without chemotherapy. -
K Mattson, LR Holsti, P Holsti, M Jakobsson, M … - Eur J Cancer Clin Oncol, 1988 - ncbi.nlm.nih.gov
1: Eur J Cancer Clin Oncol. 1988 Mar;24(3):477-82. Inoperable non-small
cell lung cancer: radiation with or without chemotherapy. ...

… for locally advanced inoperable non-small-cell lung cancer: radiation therapy oncology group … -
JS Lee, C Scott, R Komaki, FV Fossella, GS Dundas, … - Journal of Clinical Oncology, 1996 - jco.ascopubs.org
... Concurrent chemoradiation therapy with oral etoposide and cisplatin for locally
advanced inoperable non-small-cell lung cancer: radiation therapy oncology ...

Increased risk of lung cancer after breast cancer radiation therapy in cigarette smokers. -
AI Neugut, T Murray, J Santos, H Amols, MK Hayes, … - Cancer, 1994 - ncbi.nlm.nih.gov
Comment in: Cancer. 1994 Mar 15;73(6):1541-3. Increased risk of lung cancer
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… radiation therapy and concurrent chemotherapy in limited small-cell lung cancer: a randomized study -
B Jeremic, Y Shibamoto, L Acimovic, S … - Journal of Clinical Oncology, 1997 - jcojournal.org
... Initial versus delayed accelerated hyperfractionated radiation therapy and concurrent
chemotherapy in limited small-cell lung cancer: a randomized study. ...

Source: Google Scholar

Jefferson researchers show chemotherapy and radiation together extend lung cancer patients' lives

(PHILADELPHIA) Chemotherapy given at the same time as radiation therapy can help patients with a certain type of lung cancer live nearly 50 percent longer than they might have otherwise if the same treatment was given differently, according to an international team’s analysis of several trial results.

Walter Curran Jr., M.D., professor and chair of Radiation Oncology at Jefferson Medical College of Thomas Jefferson University and Jefferson’s Kimmel Cancer Center in Philadelphia, led one of six trials comparing the effectiveness of giving chemotherapy at the same time as radiation therapy versus giving radiation first, followed later by chemotherapy, to treat locally advanced non-small cell lung cancer (NSCLC).

According to Dr. Curran, there had been some controversy over whether simultaneous administration of chemotherapy and radiation for such cases was better than sequential delivery. In the United States, chemotherapy and radiation together have become the standard, whereas in other areas, such as Europe, for example, this has not been the case.

To try to resolve the matter, the International NSCLC Collaborative Group examined the results of more than 1,200 patients from six trials. The researchers found that the five-year survival rate was 10.6 percent with sequential therapy, while 15.1 percent with concurrent treatment. Dr. Curran presented the results recently at the meeting of the American Society for Therapeutic Radiology and Oncology in Los Angeles.

“That means a relative increase of nearly 50 percent,” notes Dr. Curran, who led the Radiation Therapy Oncology Group (a Philadelphia-based cooperative clinical trials organization) trial. “We’ve demonstrated that the magnitude of benefit is observable in many studies, regardless of the regimen. I think it will be as persuasive as any data that this will change not only the tumor control rate but the chance for a long-term cure.”

Dr. Curran explains that the only difference in the two treatments is that radiation is begun at another time. The drugs and radiation techniques are the same. “You’re changing the first day of radiation from day 40 to day one, for example, and as a result, are changing the number of five-year survivors by between 40 percent and 50 percent,” he says. According to these findings, theoretically, if there were 50,000 patients, approximately 5,000 who received sequential therapies would be alive in five years, and with concurrent, about 7,500.

“It is a new standard of care,” he says about the results. “It’s relatively broadly adopted in this country, but across the world, it hasn’t been. This will be a very persuasive argument.”

 

 

 
 
 
 
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